The study is to analyze the status of pesticide residues in large-scale planting vegetables around the city (taking a district of Guiyang for example). Gas chromatography was used to quantitatively analyze 17 kinds of pesticides’ residue of organic phosphorus, organochlorine and pyrethroid in 7 vegetable bases. The international food standard was used to evaluate the safety of the vegetables. The results showed that three kinds of pesticides (chlorothalonil, fenpropathrin and chlorpyrifos) were detected at different degrees in the vegetable samples with an average detection rate of 6.63%. The highest detection rate was chlorothalonil (9.84%), and the detection rate of fenpropathrin was the second (8.2%), and the detection rate of chlorpyrifos was the lowest (1.83%). According to the national food safety standards, without the determination of chlorpyrifos, the other two pesticides’ residue did not exceed the standard. The quarterly detection rate of the year was the highest in the third quarter (15.68%), followed by that of the fourth quarter (15%). The 109 vegetable samples tested were classified according to 6 categories, the detection rate from high to low was bean vegetables (33.34%) > solanaceous vegetables (21.43%) > melon and fruit vegetables (17.06%) > leaf vegetables (3.13%). The vegetable samples’ ($\overline{IFS}$) was <<1. In 2017, pesticides had no impact on the seven vegetable bases in the region, and the detection rate of pesticide residue of vegetables was safe and acceptable to consumers. The research could provide some data for the quality and safety control in local vegetable production, thus ensuring the healthy diet for local residents．