Toxic Effects on Paramecium caudatum: Tetracycline and Tetracycline Hydrochloride

陈瑛

Chinese Agricultural Science Bulletin ›› 2018, Vol. 34 ›› Issue (24) : 46-49. DOI: 10.11924/j.issn.1000-6850.casb17060115

Toxic Effects on Paramecium caudatum: Tetracycline and Tetracycline Hydrochloride

  • 陈瑛
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Abstract

The aim of this research is to discuss the acute and chronic toxic effects of tetracycline (TC) and tetracycline hydrochloride (HTC) on Paramecium caudatum , and preliminarily assess the potential threat of tetracycline antibiotics to aquatic organisms. 24h- lethal concentration 50% (LC 50) and the lowest observed effect concentration (LOEC ) of TC and HTC onParamecium caudatum were tested.LOEC was used in the stress test. 15-day monoclonal growth curve ofParamecium caudatum was investigated. The results were as follows: 24 h-LC 50 of TC was 52.36125 mg/L andLOEC was 15.19917 mg/L. 24 h-LC 50 of HTC was 50.24583 mg/L, LOEC value was 24.67175 mg/L. 15- day chronic toxic test showed that the two kinds of antibiotics had significant inhibitory effects on 15-day monoclonal growth curve ofParamecium caudatum . The increase rate of population declined and the numbers of individuals reduced. These results suggested that tetracycline and tetracycline hydrochloride had acute and chronic toxicity on single-cell animal. We should make a definite standard for using and emission, and monitor and control the pollution of TC and HTC.

Key words

Tetracycline; Tetracycline hydrochloride; Paramecium caudatum; Toxicity;Lethal concentration 50; Lowest observed effect concentration.

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陈瑛. Toxic Effects on Paramecium caudatum: Tetracycline and Tetracycline Hydrochloride. Chinese Agricultural Science Bulletin. 2018, 34(24): 46-49 https://doi.org/10.11924/j.issn.1000-6850.casb17060115

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