Two F1 (HZ and ZH) and one F2 hybrid cohorts between the Peruvian scallop, Argopecten purpuratus, and the bay scallop, A. irradians irradians were constructed and compared with their inbred cohorts (HH and ZZ) for the further study of the hybrid heterosis. The results showed that the fertilization rate, hatching rate, and larval survival rate of F2, ZH and HZ were higher than those of ZZ and HH, although the initial D-larvae shell height of F2 was significantly smaller than those of F1 cohorts. At harvest, the shell height, body weight and adductor muscle weight of F2 cohorts were smaller than F1 cohorts but significantly larger than inbred cohorts. It was thus possible to select strains with improved performance from hybrids.