The effect of different mixture ratios of two high molecular polymers SAP and PAM on soil moisture content, growth and yield of wheat in the potted experiment were studied, provides the theory basis for water-saving technology of applying combined SAP with PAM. The results showed that, during the whole growth period of wheat, the soil moisture content all prove to be SAP+PAM > PAM > SAP > CK. Compared with CK, when the soil water content at high level, the increment of different treatments ranged from 3.98% to 6.86%, and when it was at low level, the increment ranged from 13.6% and 64.78%, and the increment was the highest in SAP+PAM treatment, providing an information that SAP and PAM could reduce soil moisture evaporation, especially the SAP+PAM treatment was more obvious. The roots growth during the whole growth period of SAP treatment was not sharp, but had effect during the wheat seedling growth stage. Dry weight of shoot, root and root to shoot ratio of PAM treatment were the highest from anthesis to mature growth stage, proving that PAM could accelerate the growth of wheat in the late period of wheat. Single application of SAP, PAM and their compound all improved the wheat yield, compared with CK, the increment were 10.3%, 19.09% and 16.44% separately. The PAM treatment improved wheat yield mainly through increasing the grain weight, while combination treatment mainly through increasing the grain number per spike.