For the amino acid organic wastewater treatment as well as reuse of resources providing a theoretical reference. Based on amino acid-rich organic wastewater pollution increasing in recent years, Experiment selection of three natural mineral-type adsorbents to research the characteristics of adsorption and desorption of Lysine, Experiment used temperature shock absorption batch, Ninhydrin colorimetric determined Lysine and calculated by subtraction. Experiment also used Langmuir, Freundlich equation fitted. The results showed that three natural mineral-type adsorbents’ maximum adsorption of Lysine (Qm) expressed that Zeolite>Bentonite>Diatomite; Adsorption binding energy (K value) expressed that Diatomite>Bentonite>Zeolite; 1/N value expressed that Zeolite>Bentonite>Diatomite. Desorption rate of Lysine expressed that Zeolite>Diatomite>Bentonite, lag degree was opposite. Therefore, in order to get a large number of adsorption, and to use what was deserted again, it’s best to select Zeolite, and if in order to get a good adsorption and hold stability to prevent pollution, it’s best to select Bentonite.