In order to evaluate the environmental quality of heavy metal Pb in the surface soil and stream sediment in wastewater irrigation area of Baotou southern suburbs (WIBS). Samples were collected by using linear, profile-based and quincunx to determine the content of Pb in stream sediment and soil in different locations and regions, to analyze effects of Pb on the ecological environment, and the soil environmental quality in the research area. The results showed that the content of soil Pb in the WIBS was larger than 1.25 times of the farmland in groundwater irrigation in Baotou northern suburbs. The highest content of Pb in the main inundation sewage drainage of the research area was 565.40 mg/kg, and the highest content of soil Pb in the WIBS was 22.12 mg/kg, the average value was 19.46 mg/kg, the maximum monomial pollution index of Pb growing crop and vegetables were 0.28 and 0.44, and pollution index (Pi) was less than 0.7. Composite index of potential ecological risk was 41.18 and composite index (Ei) was less than 90. It indicated that the environmental quality of heavy metal Pb in the WIBS was lower than pollution levels and potential ecological risk degree belonged to mild. Heavy metals Pb was accumulated in the WIBS as human activities, people should pay attention to lead pollution with potential ecological risk.