Rice blast is one of major diseases in rice production in Guangxi. In order to identify the resistance or susceptibility of new varieties and select some resistant breeding materials, natural nursery was established in Cenxi. New rice varieties which provided by national rice regional trial, Guangxi rice regional trial and some breeding materials were tested in Cenxi nursery. The results showed that, there was no variety resistant to rice blast in 1171 new varieties, only few varieties were moderate resistant to rice blast, most of them were susceptible or highly susceptible. There were 82 lines highly resistant in 11236 breeding lines, 473 lines were resistant and 987 lines were moderate resistant. Some resistant materials were selected and applied for breeding program. Natural nursery was not only applied for monitoring the resistance of popular varieties, but also used as resistant breeding base.