Foot-and-mouth diseasesincluding seven main blood serums, which has listed one of the most important infectious disease by OIE and our Government. recent years, it frequently breaks out ,and seriously threat Animal Production and human -self security, because it has many subtype, strong antigenic variation microorganism and wide host range.Foot-and-mouth ecological and common heathy meaning already acquired highly concern of mankind.The Paper has summarized the infection mechanism and some diagnosis and control measures of FMD.