To cultivate high-quality talents with innovative spirit and practical ability, this article was based on the concept of Outcome Based Education (OBE), focused on ability based guidance and multi-level learning, and constructed a comprehensive for Bartending and Flower Arrangement Practice course that promoted the integration of students’ moral, intellectual, physical, aesthetic, and labor education. The key points of curriculum system construction included five key aspects: learning outcomes, learning objectives, curriculum system, teaching strategies, and curriculum evaluation. In teaching practice, its comprehensive implementation strategies included designing interdisciplinary projects that allow students to experience the integration of education, culture, art, and other fields in practice, such as creating educationally meaningful flower arrangement and cocktail making works by combining knowledge from history, culture, art, and other fields; using an evaluation system to assess students’ professional skills, moral literacy, innovation ability, and work attitude in flower arrangement and bartending; establishing a school community cooperation mechanism to jointly create an educational environment conducive to the development of students’ five educations. This article provides a reference for the construction of a course system related to bartending and flower arrangement.