一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验

曹晋良,韩建荣

食用菌学报. 2017, 24(02): 71-74

食用菌学报 ›› 2017, Vol. 24 ›› Issue (02) : 71-74. DOI: 10.16488/j.cnki.1005-9873.2017.02.16
研究论文

一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验

  • 曹晋良,韩建荣?
作者信息 +

Evaluation of a Coprinus comatus Fruit Body for Sub-acute Toxicity in Mice

  • CAO Jinliang,HAN Jianrong*
Author information +
History +

摘要

以小鼠为受试动物评价一株野生毛头鬼伞(Coprinus comatus)菌株ZMM-3人工栽培子实体的食用安全性,结果在高、 中、低(5000、500、50 mg/kg·d)剂量组实验中小鼠全部健活,体征、体重、行为、外观、脏器系数、血液生理生化指标、脏器结构均无明显异常,表明供试毛头鬼伞子实体对小鼠没有亚急性毒性.

Abstract

Organ coefficients (lung, kidney, heart, spleen, liver), hematological criteria and various biochemical parameters were monitored in mice administered 50, 500 and 5000 mg/kg·d of a powdered Coprinus comatus fruit body (designated ZMM-3) collected from the wild.No abnormal physical signs,changes in behavior, body weight, organ coefficients, and hematological and biochemical parameters were observed, indicating the absence of any obvious sub-acute toxicity.

关键词

野生毛头鬼伞

/ 亚急性毒性 / 脏器结构

Key words

Coprinus comatus

/ sub-acute toxicity / organ coefficient

引用本文

导出引用
曹晋良,韩建荣. 一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验. 食用菌学报. 2017, 24(02): 71-74 https://doi.org/10.16488/j.cnki.1005-9873.2017.02.16
CAO Jinliang,HAN Jianrong. Evaluation of a Coprinus comatus Fruit Body for Sub-acute Toxicity in Mice. Acta Edulis Fungi. 2017, 24(02): 71-74 https://doi.org/10.16488/j.cnki.1005-9873.2017.02.16

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